Ayako Rokkaku was born in 1982 in Chiba, Japan. She is a self-taught painter, and started creating her work in 2002. The following year, Rokkaku won the Illustration Prize at Kaikai Kiki's Geisai art fair, the biannual Tokyo art fair founded by Japanese artist Takashi Murakami. In 2006, she was awarded the prestigious Akio Goto Prize at the same fair.
Since 2003, Rokkaku has risen in international popularity and has held exhibitions in galleries in the Netherlands, Denmark, Germany and Slovakia. Rokkaku's work has been acclaimed in the secondary market and often reaches six-figure prices.