While attending the University of Michigan in 1974, Niagara and Mike Kelley formed Destroy All Monsters. The band, known to fans as DAM, was active until 1985, earning international recognition due largely to the presence of former members of The Stooges and the MC5. Later, she fronted the supergroup Dark Carnival (with Stooges guitarist Ron Asheton and his brother Scott Asheton, Stooges drummer).
Niagara utilized art school experience in creating album and promotional art for Destroy All Monsters, Dark Carnival, and other acts. Combining collage and pop iconography, Niagara's style began to take shape, and by the early 1990's she presented her work in galleries and cafes around Detroit.
